- Company News
Ergothioneine is a naturally occurring diet-derived thiol/thione antioxidant found in mushrooms, some bacteria and certain foods. Human and animal studies show that the body actively accumulates ergothioneine via the OCTN1 transporter, especially in tissues exposed to high oxidative stress, such as bone marrow, liver and the lens of the eye. In vitro and in vivo…
- Company News
Epirubicin hydrochloride (CAS 56390-09-1) is a potent anthracycline antineoplastic agent and the 4’-epimer of doxorubicin. It is widely used, often as epirubicin, in combination chemotherapy regimens for breast cancer and other solid tumours. As with other anthracyclines, epirubicin intercalates into DNA and inhibits topoisomerase II, leading to DNA strand breaks and apoptosis in rapidly dividing…
- Company News
Ectoin is a smart, multi-functional osmolyte originally discovered in extremophile microorganisms that live in very harsh environments such as salt lakes and deserts. As an osmolyte, ectoin helps cells maintain their optimal water balance and protects cellular structures against stress. This same property makes ectoin a powerful active for hydration, barrier support and sensitive-skin care.…
- Company News
Doxorubicin hydrochloride (CAS 25316-40-9) is a classic anthracycline antitumor antibiotic widely used in chemotherapy for a variety of solid and hematologic malignancies, including breast cancer, lymphomas and leukemias. It is isolated from Streptomyces peucetius and is known for its characteristic red colour and high cytotoxicity. On the TCS INDUSTRIES LIMITED website, Doxorubicin HCl 25316-40-9 is…
- Industry News
Making a case for GMP certification of an excipient manufacturer should be a straightforward exercise since the benefits appear so clear cut and regulatory guidance in the EU underscores the value of certification. Specifically, Chapter 3 of the EMA Guidance on formalised risk assessments to determine the appropriate GMP for a pharmaceutical excipient states that…