Product name: Hard Fat
Synonyms: Hydrogenated vegetable oil base; Suppository fat base
CAS: — (mixture)
MF: Mixture of triglycerides of saturated fatty acids
MW: —
Hard fat is a semi-synthetic mixture of saturated triglycerides designed as a stable, well-defined lipophilic base for suppositories and certain topical or oral solid dosage forms.
It exhibits sharp melting profiles close to body temperature, providing rapid melting and release of active drugs without leaving irritating residues.
Hard fat offers good oxidative stability, compatibility with many lipophilic APIs, and reliable molding and demolding performance in industrial production.
It is widely used as a pharmacopeial-grade suppository base (e.g. Witepsol-type) for rectal and vaginal dosage forms and can also serve as a structuring agent in ointments and creams.
Consistent polymorphic behavior and narrow specification ranges ensure reproducible product quality and performance.
Hard Fat – Suppository Base & Lipophilic Carrier for Solid Dosage Forms
